NCT05889091NARecruiting
A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment
Memorial Sloan Kettering Cancer Center
Start Date
5/16/2023
Completion Date
5/16/2027
Summary
The purpose of this study is to find out whether the fat ALT flap procedure is a safe and practical option for reducing neck morbidity in HNSCC patients following cancer treatment of the neck. Neck morbidity after radiation therapy and surgery includes difficulty swallowing, neck or shoulder pain, stiffness, swelling, or changes to the appearance of the treated area. In addition, the researchers will find out whether the study procedure is effective at reducing neck morbidity and improving quality of life after cancer treatment. The researchers will measure quality of life by having participants answer questionnaires.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Patients 18 years or older
* Diagnosed with HNSCC (e.g., oropharyngeal, hypo/laryngeal SCC)
* Primary treatment is with radiotherapy with or without chemotherapy
* Salvage neck dissection is subsequently indicated for persistent or recurrent, nonmucosal disease in cervical lymph nodes
* At the time of salvage neck dissection additional flap coverage is indicated to improve carotid coverage or replace missing skin
Exclusion Criteria:
* Patients with primary site mucosal recurrence in addition to neck disease
Interventions
OTHER
HRQOL instruments
OTHER
LENT SOMA instrument
Conditions
Head and Neck Squamous Cell Carcinoma
Locations
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York 10065
United States