Minimally Invasive Esophagectomy Pain Control Trial
Start Date
4/26/2022
Completion Date
2/1/2027
Summary
A pilot randomized controlled trial comparing intercostal nerve blocks, cryo-ablation plus intercostal nerve blocks, and serratus plane catheter plus intercostal nerve blocks in patients undergoing esophagectomies with minimally invasive thoracic approaches.
Detailed Description
Pilot study planned to consent 30 patients in total with a projected study timeline of 2-3 years for completion. Participants will be enrolled in the study and randomized in their preoperative clinic visit. On the day of surgery, they will receive the intervention they were randomized to. 10 patients will be randomized to the intercostal block group, 10 patients will be randomized to the cryo-ablation plus intercostal block group, and 10 patients will be randomized to the serratus plane catheter plus intercostal block group. They will be followed throughout their hospital stay until discharge for data collection purposes. Once the patient is discharged from the hospital, post-operative follow-up in the Swedish Thoracic Surgery Clinic will be collected up to 1 year post-operatively.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Local intercostal nerve block
Cryo-analgesia and intercostal nerve block
Serratus plane catheter blocks and intercostal nerve blocks
Thoracic epidural catheter
Conditions
Locations
Swedish Cancer Institute
Seattle, Washington 98104
United States