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NCT05935241NARecruitingAccepts Healthy Volunteers

mPATH for Low-income Older Adults

Johns Hopkins University

Start Date

5/30/2024

Completion Date

12/31/2029

Summary

Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults. The study aims to test the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in low-income older adults.

Detailed Description

Low-income older adults (LIOA) are a population at higher risk to develop Alzheimer's disease and related dementias (ADRD) and sleep disturbances. Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in LIOA. The growing wearable device and mobile Health (mHealth) provide an innovative approach to deliver individually tailored physical activity interventions at home with flexible schedules to overcome barriers to physical activity in LIOA. In addition, limited research has examined if physical activity interventions impact the individual's Amyloid/Tau/ Neurodegeneration (ATN) Alzheimer's disease biological state and whether physical activity may promote cognition through impacting sleep and AD pathology. This randomized controlled trial is designed to examine the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in LIOA. mPATH is a personalized physical activity intervention that includes personalized physical activity plans and training sessions, exercise at home by following personalized exercise videos, and biweekly phone coaching over 24 weeks, supported by wearable devices-enabled mHealth strategies. mHealth strategies and exercise videos will be used to support participant's physical activity during 6-12months.

Eligibility Criteria

Age Range: 65 years to No maximum

Inclusion Criteria: * self-reported difficulty of sleep * lack of physical activity/exercise * low household income * capacity for moderate intensity exercise Exclusion Criteria: * untreated sleep apnea * severe depression or anxiety * dementia * history of neurologic or psychiatric disorders, neurodevelopmental impairment, traumatic brain injury * current enrollment in another clinical trial

Interventions

BEHAVIORAL

mPATH

OTHER

Attention Control

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Conditions

Sedentary TimeInsomniaCognitive Decline

Locations

The Johns Hopkins University, School of Nursing

Baltimore, Maryland 21205

United States