Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
Start Date
9/1/2023
Completion Date
8/31/2027
Summary
Investigators will test the effectiveness of adaptive strategies on timely adoption of cervical cancer treatment in Botswana using a pragmatic trial design.
Detailed Description
Investigators will test the effectiveness of adaptive strategies on timely adoption of cervical cancer treatment in Botswana using a hybrid (type III) and pragmatic Sequential Multiple Assignment Randomized Trial (SMART) design. The adaptive strategies are designed to target patient- and system-level determinants identified in preliminary data, including delayed communication of results, individual and structural barriers to accessing treatment, and suboptimal care coordination between referring and cancer treatment clinics. The strategies draw upon key principles in behavioral economics and are supported by systematic evidence of the effectiveness of nudge strategies in preventive, HIV, and cancer care. The overarching rationale for the study is that enhancing coordination, communication, and navigation through centralized outreach and nudge strategies will increase timely treatment adoption and be scalable and sustainable in the long-term.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Clinic Outreach
Enhanced Outreach
Low-Touch Strategy
High-Touch Strategy
Conditions
Locations
University of Pennsylvania
Philadelphia, Pennsylvania 19104
United States
Nyangabgwe Referral Hospital
Francistown, North-East District
Botswana
Princess Marina Hospital
Gaborone,
Botswana