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NCT05961800NARecruiting

Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

University of Pittsburgh

Start Date

7/5/2023

Completion Date

6/1/2028

Summary

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).

Detailed Description

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a commonly-performed nerve block used to diagnose and treat chronic low back pain. Patients scheduled for lumbar medial branch blocks as part of routine clinical care will arrive to clinic prior to the block for quantitative sensory testing procedures that measure CNS pain modulation. Patients will then undergo treatment as usual with their block, subsequently reporting low back pain intensity in a pain diary.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Scheduled for lumbar MBB in UPMC Pain Management clinics * Age \> 18 years old * Predominantly axial chronic low back pain at least 3 months on a daily basis * Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\>3) * Low back pain intensity of \> 3/10 * Willing and able to receive study-related phone calls Exclusion Criteria: * History of spine surgery at the level of the lumbar MBB * Active worker's compensation or litigation claims * New pain and/or psychiatric treatments within 2 weeks of enrollment * Not fluent in English and/or not able to complete the questionnaires * Any clinically unstable systemic illness that is judged to interfere with the study

Interventions

BEHAVIORAL

Cutaneous Probe

BEHAVIORAL

Quantitative Sensory Testing

BEHAVIORAL

Computer Tasks

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Conditions

Pain, ChronicFacet Joint PainPain, ProceduralAnalgesia

Locations

UPMC St. Margaret

Pittsburgh, Pennsylvania 15215

United States