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NCT05968755NARecruitingAccepts Healthy Volunteers

Leveraging Chatbot to Improve PrEP in the Southern United States

Yale University

Start Date

7/13/2026

Completion Date

7/1/2027

Summary

The purpose of this study is to develop a chatbot intervention to promote PrEP awareness and uptake among Black men who have sex with men (MSM) in the Southern United States.

Detailed Description

In the United States (US), the epicenter of the HIV epidemic is in the South. The HIV-related death rate in the US South is high, but engagement with quality HIV prevention services and care is low. Although only 38% of the US population lives in the South, the region accounts for 51% of new HIV infections. Gay, bisexual, and other men who have sex with men (MSM) account for 60% of new infections among African Americans in the South. Black MSM are one of the most vulnerable groups to HIV transmission in the US. HIV testing and PrEP uptake in Black MSM, however, remain low (10%) due to multiple factors including stigma, sexual-orientation based discrimination and low PrEP awareness among Black MSM. Innovative strategies that motivate and provide guidance for PrEP among Black MSM in the US South are therefore urgently needed. Chatbot technology should be tested and implemented to help improve PrEP awareness and uptake in the US South. In this project, the investigators aim to develop and pilot test to assess the acceptability and feasibility of a chatbot for PrEP awareness and uptake relative to treatment as usual (control).

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Being cisgender Black male * Being aged ≥ 18 years * Having Internet access * Speaking English * Self-reporting condomless sex with another man in the past 6 months * Living in the U.S. South * HIV negative or untested. Exclusion Criteria: * Not residing in a U.S. Census Bureau-defined Southern state: AL, AR, DE, FL, GA, KY, LA, MD, MS, NC, OK, SC, TN, TX, VA, WV. * Having received antiretroviral therapy (ART) treatment.

Interventions

DEVICE

A chatbot designed to promote PrEP awareness and uptake for Black MSM

OTHER

General educational messages

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Conditions

HIV PreventionPrEP AwarenessPrEP Uptake

Locations

Care 4 U Community Health Center

Miami, Florida 33127

United States

Community Care Resources of FL (CCRSFL)

Pembroke Pines, Florida 33027

United States

NAESM, Inc

Atlanta, Georgia 30318

United States

RAO Community Health

Charlotte, North Carolina 28202

United States