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NCT06037941NARecruiting

Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma

Memorial Sloan Kettering Cancer Center

Start Date

9/8/2023

Completion Date

9/1/2026

Summary

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure how people respond to standard treatment for malignant pleural mesothelioma (MPM). The researchers will study how E-Nose breathprints change over time as people receive standard treatment for MPM. They will also look at how changes in people's E-Nose breathprints compare to changes in their standard imaging scans and in biomarkers of MPM in their blood.

Eligibility Criteria

Age Range: 30 years to 85 years

Inclusion Criteria: * Aged 30-85 years * No history of thoracic cancer or extrathoracic cancer potentially involving pleural metastases (i.e., breast, gastric, colon, or pancreas cancer) * Recent diagnosis of MPM * Documented, signed, and dated informed consent, obtained before any procedures, for the proposed research study, and signed standard surgical consent for surgical resection Exclusion Criteria: * Aged \<30 or \>85 years at the first outpatient visit * History of thoracic or extrathoracic cancer that puts the subject at risk for pleural or pulmonary metastases

Interventions

DIAGNOSTIC_TEST

E-Nose testing

DIAGNOSTIC_TEST

Research blood

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Conditions

Malignant Pleural Mesothelioma

Locations

Memorial Sloan Kettering Basking Ridge (Consent Only)

Basking Ridge, New Jersey 07920

United States

Memorial Sloan Kettering Monmouth (Consent Only)

Middletown, New Jersey 07748

United States

Memorial Sloan Kettering Bergen (Consent Only )

Montvale, New Jersey 07645

United States

Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent Only)

Commack, New York 11725

United States

Memorial Sloan Kettering Westchester (Consent Only)

Harrison, New York 10604

United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York 10065

United States

Memorial Sloan Kettering Nassau (Consent Only)

Uniondale, New York 11553

United States