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NCT06058169NARecruiting

Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)

Augusta University

Start Date

4/25/2025

Completion Date

9/1/2026

Summary

The purpose of this proposal is to understand how the Vibrant Health Ultimate whole-body vibration (WBV) machine affects pain and inflammation in older adults. The investigators' hypothesize that sub-acute (12 weeks) WBV will lead to improvement in the level of knee pain and improve vascular function via a decrease in systemic inflammation.

Detailed Description

Knee osteoarthritis (KO) is a leading cause of disability and medical cost. Whole body vibration (WBV) has emerged as an exercise alternative that may be more tolerable than traditional forms of exercise, such as treadmill walking/running or cycling. Similar to traditional exercise, research supports that WBV can be very beneficial for your health. In fact, a single bout of WBV increases circulating concentrations of inflammatory markers. WBV is safe and effective, WBV training has been conducted in obesity, elderly, patients with diabetes, patients with lung disease, as well as patients with knee osteoarthritis.

Eligibility Criteria

Age Range: 40 years to 75 years

Inclusion Criteria: * Symptomatic Osteoarthritic knee pain for at least 6 months. * Mean and women * Ages 40-75 years old Exclusion Criteria: * \<40 years old or \>75 years old * History of balance issues * History of falls * Epilepsy * Pregnancy * The use of whole-body vibration in the past 6 months * Previous knee surgery within last 3 years * Unable to stand for at least 20 minutes (for whole body vibration training)

Interventions

DEVICE

Sub Acute Whole Body Vibration Training

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Conditions

Whole Body VibrationOsteo Arthritis Knee

Locations

Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology

Augusta, Georgia 30912

United States