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NCT06059352Recruiting

Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder

Loma Linda University

Start Date

11/1/2023

Completion Date

12/1/2026

Summary

The proposed study aims to understand poor sleep as a possible cause to CAPD in children and adolescents with ASD (ASD+) compared to ASD youth without CAPD (ASD-), using both caregiver-report and objective clinician administered measures. Additionally, the study will aim to understand the complex relationship between CAPD, sleep, and other associated phenotypic features of ASD such as executive and psychiatric functioning.

Detailed Description

Participation will involve one assessment session approximating 4 hours including administration of neurocognitive and socioemotional measures by trained research staff. The research team then will determine which participants meet CAPD diagnostic criteria for both the SCAN-3 and RGDT tests and assign them to the ASD+ group. Participants not meeting these criteria will be assigned to the ASD- group. Following the assessment visit, all participants will then be asked to wear actigraphy monitors (comparable to overnight polysomnography) regularly for 14 days during nighttime sleep to objectively measure sleep quality.

Eligibility Criteria

Age Range: 6 years to 17 years

Inclusion Criteria: * Have diagnosis of Autism Spectrum Disorder confirmed by the Autism Diagnostic Observation Schedule and the Social Communication Questionnaire, Lifetime Version which will be filled by the parent * IQ of 50 or higher on the Abbreviated Battery IQ Score Exclusion Criteria: * No confirmed diagnosis of Autism Spectrum Disorder * History of sleep apnea * History of restless leg syndrome * History of any neurological disorders (e.g., seizures, tumors, etc.) * Significant substance use in the past six months * Inpatient hospitalization in the past three months-period

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Conditions

Central Auditory Processing DisorderAutism Spectrum DisorderSleep Disturbance

Locations

Loma Linda University Health

Loma Linda, California 92350

United States