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NCT06065228Recruiting

Therapeutic Endpoint in Pediatric IBD Conditions

Children's National Research Institute

Start Date

11/27/2023

Completion Date

12/1/2027

Summary

The purpose of this clinical study is the development of physiologic endpoint of inflammation in pediatric patients diagnosed with inflammatory bowel disease (IBD), specifically subtypes Crohn's disease (CD) and ulcerative colitis (UC). The novel medical device evaluates the patient's sensory response to each of the three sensory nerve fiber types. Data from the device provides an assessment of disease activity and a more precise approach to treatment.

Eligibility Criteria

Age Range: 6 years to 21 years

Inclusion Criteria: * Male or female ≥ 6 years of age at screening. * Documentation of an IBD diagnosis as evidenced by history Exclusion Criteria: * Documented history of eye disease precluding pupillometry * Patients who are unwilling or unable to participate due to developmental delays or ongoing psychological diagnoses.

Interventions

DEVICE

AlgometRx Nociometer

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Conditions

Inflammatory Bowel DiseasesColitis, UlcerativeCrohn Disease

Locations

Children's National Health System

Washington D.C., District of Columbia 20010

United States