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NCT06077227NARecruiting

Immersive Healing: The Therapeutic Potential of Virtual Reality

Wake Forest University Health Sciences

Start Date

12/21/2023

Completion Date

10/1/2026

Summary

Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life. The literature delineating prevalence of upper versus lower limb amputations is limited, but the prevalence of total amputations in the United States is estimated to reach 3 million individuals by 2050, with approximately 185,000 new cases annually. PLP affects 60-68% of these patients, leading to heightened levels of anxiety, depression, and reduced overall well-being.

Detailed Description

Although studies exploring the efficacy of VR therapy for PLP have reported positive outcomes, several limitations, such as small sample sizes, lack of randomization, and inconsistent treatment protocols, have impeded widespread adoption of these innovative approaches. Additionally, the literature does not sufficiently delineate which aspects of the phantom limb experience may be addressed with VR therapy. To overcome these limitations and optimize treatment efficacy, it is crucial to gain a comprehensive understanding of the phantom limb experience, including both somatosensory and kinesthesia-related symptoms. Additionally, this study will address these limitations by employing a larger sample size, rigorous methodology, and a standardized treatment protocol.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * History of major limb amputation * Age \> 18 years old * Presence of phantom limb pain or negative phantom sensation(s) Exclusion Criteria: * Active mental illness, neurological disease, or cognitive impairment that would interfere with survey completion * Those without phantom limb pain or negative phantom limb sensations * Non-English speaking

Interventions

DEVICE

virtual reality therapy

OTHER

matched control group

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Conditions

Phantom Limb Pain (PLP)

Locations

OrthoCarolina Hand Center

Charlotte, North Carolina 28207

United States