NCT06092008Recruiting
Performance of New Diagnostic Methods in Older Adults With Pneumonia
Ohio State University
Start Date
12/2/2022
Completion Date
6/30/2027
Summary
Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.
Eligibility Criteria
Age Range: 65 years to No maximum
Inclusion Criteria:
\- Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)
Exclusion Criteria:
* inability to obtain consent from the patient or an LAR
* active cancer
* organ transplant
* immunosuppression
* trauma activation
* suicidal ideation
* incarceration
* antibiotics in the last 14 days
* a separate episode of lower respiratory illness in the last 30 days
Conditions
Pneumonia
Locations
The Ohio State University
Columbus, Ohio 43210
United States