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NCT06120231NARecruiting

Pulse-Width Modulation

Dartmouth-Hitchcock Medical Center

Start Date

12/1/2023

Completion Date

10/1/2027

Summary

The overarching aim of this project is to modulate the pulse-width during stimulation of pedicle screws and record the response thresholds associated with each PWM setting. During this initial phase of the investigation, no further data will be collected.

Detailed Description

In vivo electrical stimulation of pedicle screws is a well-documented modality for evaluating potential breach of the pedicle wall. However, previous research has focused primarily on the stimulation threshold intensity required to elicit a neurophysiological response. Other stimulation parameters, such as pulse-width, remain uninvestigated. The goal is to obtain data on the pulse-width vs. CMAP relationship.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * A patient will be eligible for study participation once they have been booked for a surgery involving pedicle screw placement and intraoperative neuromonitoring. Exclusion Criteria: * The study excludes neonates, minors, pregnant women, prisoners and cognitively impaired patients.

Interventions

DIAGNOSTIC_TEST

Pulse width modulation

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Conditions

Spinal FusionSpinal Stenosis

Locations

Dartmouth-Health

Lebanon, New Hampshire 03677

United States