NCT06141447PHASE2RecruitingAccepts Healthy Volunteers

Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

University of Colorado, Denver

Start Date

5/2/2024

Completion Date

11/2/2026

Summary

The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.

Eligibility Criteria

Age Range: 18 years to 55 years

Inclusion Criteria: * clinic-based D\&E at 18 weeks gestational age and above * speaks English or Spanish Exclusion Criteria: * refuses IV * history of coagulopathy * anticoagulant use in the preceding five days * chorioamnionitis or sepsis * suspected placenta accreta spectrum * intrauterine fetal demise * multiple gestation * use of misoprostol for cervical preparation

Interventions

DRUG

Oxytocin + normal saline

DRUG

Normal saline

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Hemorrhage

Locations

Comprehensive Women's Health Center

Denver, Colorado 80230

United States