Back to Trials
NCT06165419PHASE2Recruiting

Definitive Radiation for High-Risk Spine Metastases

Stony Brook University

Start Date

12/14/2023

Completion Date

5/31/2026

Summary

This study is looking at whether patients with cancer that has aggressively spread to the spine can be treated with stereotactic body radiation therapy only and avoid a large spine surgery

Eligibility Criteria

Age Range: 18 years to No maximum

Eligible patients must have: * Any pathologically proven solid tumor diagnosis not of central nervous system origin with radiographic or pathologic evidence of metastatic disease * Metastatic spine involvement documented by imaging * Involvement of maximum 3 contiguous vertebral bodies at the index site * Intact neurologic function, or only minor neurologic deficits with muscle strength greater or equal to 4 out of 5 with or without steroids * An evaluation by an radiation oncology and orthopedic spine/neurosurgery attending * ECOG Performance Status of 0-3 Patients are ineligible if they have: * An unstable spine defined as a Spinal Instability Neoplastic Score (SINS) greater than 12 * Had previous surgery or radiation to address the target spinal metastases * Radiosensitive tumors (e.g. small cell lung cancer, lymphoma, multiple myeloma, and germ-cell tumors)

Interventions

RADIATION

SBRT to the spine

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Metastatic CancerMetastatic Lung CancerMetastatic Breast CancerMetastatic TumorMetastatic Tumor of BoneMetastatic Tumor to the SpineSpine MetastasesMetastasis

Locations

Stony Brook University Hospital

Stony Brook, New York 11794

United States