NCT06260072PHASE2Recruiting
Magnesium and Riboflavin Treatment for Post-Concussion Headache
University of Virginia
Start Date
2/10/2020
Completion Date
12/31/2025
Summary
This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.
Eligibility Criteria
Age Range: 18 years to 40 years
Inclusion Criteria:
* Seen at University of Virginia Student Health and Wellness Center or Emergency Department for Initial Visit for Concussion;
* Less than 3 days have elapsed since their injury;
* Able to swallow capsules
Exclusion Criteria:
* Concussion complicated by cranial bleed, skull fracture, additional severe injury;
* Kidney disfunction or failure;
* Significant gastro-intestinal dysfunction;
* Varsity Athlete;
* Two or more previous concussions;
* Women who are pregnant or breast feeding;
* Taking tetracycline, fluoroquinolone, iron digoxin, chlorpromazine or penicillamine
Interventions
DRUG
magnesium and riboflavin supplement
Conditions
Concussion, Intermediate
Locations
University of Virginia Student Health and Wellness Center
Charlottesville, Virginia 22903
United States