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NCT06261034Recruiting

A Study of Sex Differences in Neurocirculatory Control

Mayo Clinic

Start Date

10/29/2024

Completion Date

3/1/2027

Summary

The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).

Eligibility Criteria

Age Range: 20 years to 70 years

Inclusion Criteria: * 20-70 years of age Exclusion Criteria: * Coronary artery disease * Heart failure * Pregnancy * COPD * Diabetes * CKD * Sleep disorders other than OSA * Shift workers * Individuals who typically go to sleep after midnight * Individuals who traveled across ≥2 time zones within one week of study visits * BMI ≥40.0kg/m2 * Use of nicotine-containing products within the two years preceding study visits * Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures

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Conditions

Obstructive Sleep Apnea

Locations

Mayo Clinic in Rochester

Rochester, Minnesota 55905

United States