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NCT06261736NARecruiting

The Effectiveness of Prophylactic Antibiotics for Urethral Bulking

Atlantic Health System

Start Date

10/24/2023

Completion Date

1/1/2026

Summary

The goal of this clinical trial is to evaluate if prophylactic antibiotics in urethral bulking are effective in reducing postprocedural urinary tract infections.

Detailed Description

Urethral bulking is a minimally invasive surgical treatment option for stress urinary incontinence (SUI). One commonly reported post-procedural complication is urinary tract infection (UTI). UTI rates are variable where studies have reported rates from as low as 0% to as high as 40%. Along with this variability, the instructional inserts for various bulking agents have inconsistent recommendations for use of prophylactic antibiotics. The American Urologic Association recommends antimicrobial prophylaxis for cystourethroscopy procedures involving minor manipulation. Currently, there are no clear guidelines regarding the utility of prophylactic antibiotics for urethral bulking. The objective of our study is to determine the effectiveness of prophylactic antibiotics in urethral bulking for reducing post procedural UTIs.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patients scheduled to undergo a urethral bulking procedure * Age 18 ≥ over Exclusion Criteria: * History of recurrent urinary tract infections * Known history of urinary retention * Allergies or contraindications to multiple antibiotics * Inability to tolerate oral antibiotics * Concomitant surgical procedures at the time of urethral bulking * Pregnant or breastfeeding

Interventions

OTHER

Prophylactic antibiotics

OTHER

No antibiotics

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Conditions

Stress Urinary IncontinencePostoperative Urinary Tract InfectionUrethral Bulking

Locations

Atlantic Health

Morristown, New Jersey 07960

United States