Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)
Start Date
7/11/2024
Completion Date
10/30/2029
Summary
This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of current medications, and reporting of any adverse events related to study procedures or NA therapy if restarted. Study participation will be for approximately 2 years (to complete a total of at least 3 years of follow-up while off NA therapy, inclusive of parent study participation).
Eligibility Criteria
Age Range: 20 years to 70 years
Interventions
Non-interventional
Conditions
Locations
Research and Education Inc.
San Diego, California 92105
United States
University of Miami Miller School of Medicine
Miami, Florida 33136
United States
Infectious Disease Care
Hillsborough, New Jersey 08844
United States
The Alfred Hospital
Melbourne, Victoria 3004
Australia
Fiona Stanley Hospital
Murdoch, 6150
Australia
Prince of Wales Hospital
Shatin, New Territories
Hong Kong
Queen Mary Hospital
Hong Kong,
Hong Kong
Arensia Exploratory Medicine Moldova
Chisinau,
Moldova
Asan Medial Center
Seoul, 05505
South Korea
Changhua Christian Hospital
Changhua, 600566
Taiwan
Chia-Yi Christian Hospital
Chiayi City, 60002
Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, 80756
Taiwan
E-Da Hospital
Kaohsiung City, 82445
Taiwan
Taichung Veterans General Hospital
Taichung, 40705
Taiwan
Chang Gung Medical Foundation Linkou
Taoyuan, 33305
Taiwan
University Hospital of Wales, Cardiff
Cardiff, CF144XW
United Kingdom
Royal London Hospital
London, E11FR
United Kingdom
King's College Hospital
London, SE59RS
United Kingdom