Back to Trials
NCT06286774NARecruitingAccepts Healthy Volunteers

Sleep as a Mechanism of Change in Alcohol Use

University of Missouri-Columbia

Start Date

3/2/2024

Completion Date

5/30/2028

Summary

This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes.

Detailed Description

Heavy alcohol use is prevalent in the United States and results in significant physical and psychological burden. One in 10 adults in the United States reports binge drinking on a weekly basis, and few are willing to seek mental health treatment. Thus, additional strategies are needed to engage and treat individuals at risk for alcohol-related harm. Half of those who screen positive for hazardous drinking report clinically significant symptoms of insomnia. Insomnia tends to be less stigmatized than other mental health disorders, and it is one condition for which the field has highly efficacious treatment. Thus, one potential strategy to engage individuals in mental health treatment and reduce the burden of alcohol use in the United States is to target insomnia. This project aims (1) to examine change in insomnia as a mediator of insomnia treatment effects on alcohol use outcomes and sex as a moderator of those effects and (2) to identify mechanisms linking change in insomnia to alcohol use outcomes. Adults who drink alcohol and have insomnia will be randomly assigned to Cognitive Behavioral Therapy for Insomnia (CBT-I, n=112) or waitlist control (WLC, n=112). Outcomes will be assessed weekly during treatment, at the end of the active intervention period (post-treatment), and at 1-, 3-, and 6-month follow-ups.

Eligibility Criteria

Age Range: 18 years to 49 years

Inclusion Criteria: * report heavy drinking in a typical week in the past month * meet DSM-5 criteria for Alcohol Use Disorder * meet DSM-5 and research diagnostic criteria for Insomnia Disorder Exclusion Criteria: * ≥50 years * unable to provide informed consent * report contraindications for CBT-I (mania or seizure disorder) * moderate to severe sleep apnea that is untreated * have symptoms requiring immediate clinical attention (e.g., psychosis, suicide plan) * are already receiving behavioral treatment for insomnia or alcohol use

Interventions

BEHAVIORAL

Cognitive Behavioral Therapy for Insomnia

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

InsomniaAlcohol; Harmful Use

Locations

University of Missouri-Columbia

Columbia, Missouri 65212

United States