A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser
Start Date
10/16/2024
Completion Date
3/1/2027
Summary
This research study aims assess whether the Difference Frequency Generation (DFG) laser could be a better alternative to the CO2 laser in terms of reduced side effects and patient downtime.
Detailed Description
The primary goal of this study is to compare the pain score and wound healing time in healthy subjects undergoing low fluence fractional ablation using the DFG and CO2 lasers. The secondary objective involves assessing the impact of each laser on dermal vasculature using an Optical Coherence Tomography (OCT) imaging system. Participants will be treated with the DFG and CO2 laser to the upper thighs. Photography, pain scores, and OCT imaging will be recorded over the course of the study visits. The investigators plan to enroll 23 healthy subjects to complete the study. Subjects must be equal to greater than 18 years old and may be any gender or Fitzpatrick skin type.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
DFG Laser
CO2 Laser
Optical coherence tomography (OCT)
Conditions
Locations
MGH Clinical Unit for Research Trials & Outcomes in Skin
Boston, Massachusetts 02114
United States