H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Ability of subject to understand, and the willingness to sign a written informed consent document and comply with requirements of the study * Stated willingness to comply with all study procedures and availability for the duration of the study * Male or Female participants ages \>18 years * MD diagnosis of Idiopathic Pulmonary Fibrosis or other progressive ILD as defined previously * DLCO\>30% and FVC\>45% * Subjects in reproductive age who are heterosexually active must use an acceptable method of contraception: condoms (male or female) with or without a spermicidal agent, diaphragm or cervical cap with spermicide, IUD, or Hormone-based contraceptive * Agreement to adhere to Lifestyle Considerations throughout study duration EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: * Active on lung transplantation list * On supplemental oxygen at rest * Evidence of an acute respiratory infection or exacerbation of pulmonary fibrosis * Known diagnosis of celiac disease or wheat or gluten allergies * Cirrhosis or active viral or non-viral hepatitis: Bilirubin, AST and ALT values higher than twice the upper range of normal, or a Child-Pugh score of 7 or more * Subjects with history of active Inflammatory Bowel Disease, dysphagia, achalasia, or difficulty swallowing capsules, tablets or pills * Subjects with significant renal impairment defined as eGFR lower than 40 ml/min. * Subjects with a baseline corrected Fridericia's QT interval (QTcF) \>450ms or baseline ECG abnormalities which, in the opinion of the study physician, are clinically significant and would place the participant at increased risk for adverse effects. * Subjects with ongoing alcohol or illegal drug use disorder * Subjects who are pregnant, lactating or attempting to conceive * Participants able to become pregnant (have not completed menopause, had a hysterectomy and/or both tubes and/or both ovaries removed) must use effective birth control methods to try and not become pregnant while participant in this study. Methods include (a) partner vasectomy, (b) bilateral tubal ligation, (c) intrauterine devices (IUDs), (d) hormonal implants (such as Implanon), or (e) other hormonal methods (birth control pills, injections, patches, vaginal rings). * Male participants able to father children with a partner able to become pregnant must agree to use effective birth control (listed above) to participate in this study. * Known allergy to hymecromone or any component thereof * Chronic therapy with medications that are known potent human UDP-glucuronosyltransferase inhibitors: canagliflozin, temazepam, tacrolimus. * Physician concern that participant may not adhere to the study protocol * Current participation in another clinical treatment trial for ILD. May participate after 12 weeks from conclusion of another treatment trial. * Changing dose of other ILD medications over the 3 months prior to baseline * Any condition(s) or diagnosis, both physical or psychological, or physical exam finding that place the participant at increased risk for adverse effects, as determined by the study physician. Participants who completed the original 12-week treatment portion of the SOLIS study prior to the implementation of the optional 12-week extension phase may have the option to re-enroll under the amended protocol, after an appropriate washout period of up to 6 months. Participants will be re-screened as per criteria above to ensure that eligibility criteria continue to be met. Once eligibility is confirmed, participants can complete the 12-week treatment and optional 12-week extension for a maximum treatment period of 24 weeks. These re-enrolled participants will be enrolled as new participants and receive a different screening number to differentiate them from the original enrollment.