NCT06339203NARecruiting

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

Loma Linda University

Start Date

6/5/2024

Completion Date

12/1/2026

Summary

This investigator-initiated, open-label, randomized controlled trial will explore the effects of two treatment arms, comparing standard treatment with normal saline against Irrisept, a jet lavage solution containing a low concentration of Chlorhexidine Gluconate (CHG) at 0.05% in 99.95% sterile water for irrigation. The study aims to evaluate the impact on postoperative wound healing in patients who have undergone cesarean delivery.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Age 18 or older * Singleton pregnancy * Planned cesarean delivery at gestational age 37 weeks or later at Loma Linda University Children's Hospital * Planned post-operative follow up with Loma Linda OBGYN * Speak English or Spanish * At least one of the following medical complications: Obesity BMI\>= 30kg/m2, Diabetes, Spontaneous rupture of membranes, Intraamniotic infection Exclusion Criteria: * Emergency cesarean delivery

Interventions

DEVICE

Irrisept

DRUG

Normal Saline

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Cesarean Section ComplicationsCesarean Section; Infection

Locations

Loma Linda University

Loma Linda, California 92354

United States