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NCT06380075NARecruiting

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

University of Wisconsin, Madison

Start Date

8/29/2024

Completion Date

12/1/2026

Summary

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs). Participants will: * undergo pupillary dilation * have photographs taken of the inside of the eyes using three different cameras

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial * Participants that are willing to participate as evidenced by signing the written informed consent Exclusion Criteria: * Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation * Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring * Patients with advanced IRDs who are unable to fixate for imaging * Patients unable to tolerate ocular imaging * Patients who do not wish to participate

Interventions

DEVICE

Spectralis FAF imaging

DEVICE

Optos imaging

DEVICE

Clarus imaging

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Conditions

Retinal Disease

Locations

Department of Ophthalmology and Visual Sciences

Madison, Wisconsin 53705

United States