NCT06420219Recruiting
An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence
University of Southern California
Start Date
3/25/2024
Completion Date
3/25/2029
Summary
This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.
Detailed Description
PRIMARY OBJECTIVE: I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes. OUTLINE: This is an observational study. Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Diagnosis/disease status: New diagnosis of head and neck cancer
* Allowable type and amount of prior therapy: No prior treatment
* Age ≥ 18 years.
* Ability to understand and the willingness to sign a written informed consent.
Exclusion Criteria:
* Patients who have had treatment of head and neck cancer
Interventions
OTHER
Non-Interventional Study
Conditions
Head and Neck Carcinoma
Locations
USC / Norris Comprehensive Cancer Center
Los Angeles, California 90033
United States