Back to Trials
NCT06451874NARecruiting

Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome

VA Office of Research and Development

Start Date

7/1/2025

Completion Date

12/31/2029

Summary

This study will begin to evaluate personalized preventative dementia treatments for Veterans at risk for developing dementia. The investigators will target Veterans with Motoric Cognitive Risk syndrome (MCR), which is characterized by slow gait speed and cognitive concerns (e.g., problems with memory or concentrations).

Detailed Description

This study will involve therapeutic exercise treatments for Veterans with pre-clinical dementia syndrome. Participants will either participate in functional power training, music-based walking training, or a combination of both. The study will use a sequential multiple assignment, randomized trial (SMART) design. Successful completion of this study will lay the foundation for subsequent research trials, contributing to valuable evidence for personalized rehabilitation medicine for older Veterans.

Eligibility Criteria

Age Range: 65 years to No maximum

Inclusion Criteria: 1. Age 65 2. Receiving VA primary care 3. Community-dwelling 4. Motoric Cognitive Risky Syndrome i. Slow gait speed ii. Subjective cognitive concerns/complaints Exclusion Criteria: 1. Non-English speaking 2. Presence of a terminal disease 3. Major medical problem 4. Myocardial infarction or major surgery in the previous 3 months 5. 3-point walking pattern 6. Dementia diagnostic 7. Mobility disability

Interventions

BEHAVIORAL

Functional Power Training (FPT)

BEHAVIORAL

Music-Based Digital Therapy (MBDT)

BEHAVIORAL

FPT + MBDT

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Motoric Cognitive Risk Syndrome

Locations

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts 02130-4817

United States