Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders
Start Date
4/21/2025
Completion Date
12/31/2030
Summary
This study for the conservative management of placenta accreta spectrum disorders (PAS), which are a major cause of maternal morbidity and mortality. The most common management strategy for PAS in the United States is a preterm cesarean-hysterectomy. However, accumulating data show that conservative management is safer and is preferred by some patients. In selected participants (n=15) who desire uterine preservation, the investigators provide the option of conservative management, which will be defined as leaving the placenta in the uterus after delivery of the infant. This is a single-arm single-site pilot study where all participants will be carefully monitored during a standard postpartum inpatient stay and with outpatient follow-up until the uterus is empty.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Conservative/Expectant Management
Conditions
Locations
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania 19104
United States