NCT06513208PHASE4RecruitingAccepts Healthy Volunteers
Ketorolac Effects on Post-operative Pain and Lumbar Fusion
University of Maryland St. Joseph Medical Center
Start Date
1/1/2026
Completion Date
6/1/2027
Summary
A double blind prospective randomized trial of IV ketorolac vs. placebo in management of patients undergoing lumbar one or two level spinal fusions.
Eligibility Criteria
Age Range: 18 years to 85 years
Inclusion Criteria:
* 18-85 years old (inclusive)
* Elective posterior lumbar instrumented fusion
* One or two level fusion
* Consent to participate in study and willing to adhere to study follow up
* English proficiency
Exclusion Criteria:
* \< 18 or \> 85 years old
* History of renal failure, dialysis, or creatinine over 1.50 mg/dl
* Active or recent smoker (active within past 6 months)
* Revision surgery
* Auto/worker compensation
* Active cancer or history of chemotherapy in past 6 months
* Active narcotic use within 3 months of surgery date
* Infection at operative levels
* Any allergies to NSAIDs or Opioids
Interventions
DRUG
Ketorolac Tromethamine
DRUG
Placebo
Conditions
Lumbar Spinal Fusion
Locations
University of Maryland St. Joseph Medical Center
Towson, Maryland 21204
United States