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NCT06556602NARecruitingAccepts Healthy Volunteers

Methadone Patient Access to Collaborative Treatment

University of Arizona

Start Date

2/5/2026

Completion Date

6/30/2029

Summary

The trial of Methadone Patient Access to Collaborative Treatment (MPACT) will establish the impact of the intervention on patient outcomes of methadone treatment retention and in treatment overdose. It will also establish the impact of patient and staff trauma symptoms and clinic practice change on MPACT intervention implementation.

Detailed Description

This MPACT trial will involve finalizing the refined MPACT intervention (materials, training) and conducting a Hybrid Type 1, 15-month cluster randomized controlled trial in 30 clinics with 600 patients (20/clinic) and 480 staff (18/clinic) to assess MPACT effect on patient outcomes and examine the relationship between staff trauma outcomes and MPACT implementation. R33 Specific AIMS: AIM 1: Quantify the effects of MPACT on methadone treatment (MMT) practice change and opioid treatment program (OTP) culture. AIM 2: Determine the efficacy of MPACT on MMT retention, in-MMT overdose and patient and staff post traumatic stress symptoms (PTSS) outcomes. AIM 3: Evaluate the effect of patient and staff trauma symptoms on primary outcomes and staff MPACT implementation.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Staff providing methadone treatment services at the enrolled opioid treatment programs Exclusion Criteria: * Patients receiving methadone treatment at the enrolled opioid treatment programs

Interventions

OTHER

MPACT

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Conditions

Opioid Use DisorderStaffPatients

Locations

University of Arizona College of Nursing

Tucson, Arizona 85714

United States