Myo-inositol During Pregnancy to Prevent Gestational Diabetes
Start Date
3/1/2025
Completion Date
6/30/2027
Summary
Myoinositol is an insulin-like compound that is present in both plant and animal cells. Humans synthesize it naturally, but it is also obtained in our diet. It works through an intracellular signaling pathway to increase insulin sensitivity. Myoinositol has been used as an over-the-counter (OTC) supplement in the management of polycystic ovarian syndrome due to this effect. Myoinositol has also been shown to improve glycemic profiles in pregnant euglycemic women and well as improve insulin sensitivity in pregnant patients with gestational diabetes mellitus (GDM). This is a double blind RCT offering myo-inositol or placebo to those who are eligible and enrolled.
Eligibility Criteria
Age Range: 18 years to 45 years
Interventions
Myo-inositol
Myo-inositol placebo
Conditions
Locations
Tufts Medical Center
Boston, Massachusetts 02111
United States