NCT06585631NARecruitingAccepts Healthy Volunteers

The Collaborative Care PrTNER Study

Children's Hospital of Philadelphia

Start Date

1/2/2025

Completion Date

6/30/2028

Summary

A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk for HIV) and decrease viral load (for those living with HIV) among young aged 15 to 29 through engagement in SU treatment.

Detailed Description

The Collaborative Care (CC) PrTNER is a multi-component intervention developed by members of the research team specifically for young men aged 15 to 29 who are at-risk for or living with HIV. This model moves beyond the individual to consider the broader context in which, substance use (SU), and HIV risk are (re)produced. Enhanced models that integrate SU treatment into HIV and PrEP primary care services (using a collaborative care approach that incorporates feedback from a psychiatrist and support from a peer coach) are needed to address the nuance of substance use in this population. We, therefore, are proposing to conduct a randomized trial to evaluate an integrated collaborative care model (CC PrTNER).

Eligibility Criteria

Age Range: 15 years to 29 years

Inclusion Criteria: Aim 1: * 15-24 years old; * Cisgender male; * History of condomless sex; * Moderate-to-high risk SU behaviors based upon a Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) score ≥2, * Living in Philadelphia, PA or Baltimore, MD, and surrounding areas; * Able to read and write in English Aim 2: * 15-29 years old; * Cisgender male; * Living with a diagnosis of HIV; * CRAFFT score ≥2, * Living in Philadelphia, PA or Baltimore, MD, and surrounding areas; * Able to read and write in English Aim 3 • All randomized study participants will be included in Aim 3. Exclusion Criteria: Aim 2: * Participants will be excluded if they are: * Assigned female sex at birth * Identify as transgender * Outside the age criteria (\<15 or \>29 years old) * Cognitively unable to complete study requirements * Living outside of the two geographic areas * Do not screen positive for SU * No prior substance use history * No prior condomless sex; * Unable to read or write in English, * Plan to move in the next 12 months.

Interventions

BEHAVIORAL

CC PrTNER

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

HIVSubstance Use DisordersSubstance UseAIDS

Locations

Johns Hopkins Center for Adolescent and Young Adult Health

Baltimore, Maryland 21205

United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania 19146

United States