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NCT06594913RecruitingAccepts Healthy Volunteers

Eating Disorders Genetics Initiative 2

University of North Carolina, Chapel Hill

Start Date

10/28/2024

Completion Date

9/1/2027

Summary

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Eligibility Criteria

Age Range: 12 years to 99 years

Inclusion Criteria: * A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms * Age 12-99 years, depending on country. (US enrollment age is 18-99) Exclusion Criteria: * History of subthreshold disordered eating behaviors.

Interventions

OTHER

Eating disorder diagnosis group

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Conditions

Anorexia NervosaBulimia NervosaBinge-Eating DisorderAvoidant Restrictive Food Intake Disorder

Locations

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina 27599-7160

United States

QIMR Berghofer

Brisbane, Queensland

Australia

Comenzar de Nuevo

Monterrey,

Mexico

University of Otago

Christchurch, Canterbury

New Zealand

Karolinska Institutet

Stockholm,

Sweden