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NCT06624592PHASE3Recruiting

Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium

Mayo Clinic

Start Date

12/20/2024

Completion Date

11/1/2026

Summary

The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.

Eligibility Criteria

Age Range: 2 years to 7 years

Inclusion Criteria: * Pediatric patients aged 2-7 years. * Surgeries include ENT cases (i.e., tonsillectomy/adenoidectomy), ophthalmology cases (i.e., strabismus), and urology cases. * Can be outpatient or General Care inpatient procedures. * All cases must include an IV and an endotracheal tube (ETT). Exclusion Criteria: * Severe developmental/cognitive delay (unable to make eye contact, nonverbal, or inability to interact with providers for PAED scale assessment requirements) * TIVA cases. * No PIV in place during the case, planned PICU admission postoperatively. * Previous history of severe emergence delirium documented by a provider (via interventions or explicitly stated).

Interventions

DRUG

Sevoflurane

DRUG

Isoflurane

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Conditions

Delirium on Emergence

Locations

Mayo Clinic in Rochester

Rochester, Minnesota 55905

United States