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NCT06633978NARecruitingAccepts Healthy Volunteers

Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

University of California, San Francisco

Start Date

9/10/2024

Completion Date

8/1/2026

Summary

The goal of this proposed research is to collect pilot data to test the hypothesis that treatment with a novel form of closed-loop digital meditation (MediTrain) will lead to a greater magnitude of gains in cognitive abilities in patients with mild cognitive impairment (MCI), compared to OA without cognitive impairment, and will lead to improvements in quantitative measures of sleep.

Eligibility Criteria

Age Range: 60 years to 85 years

* comfortably ambulatory healthy physical condition * normal or corrected to normal visual * auditory acuity * fluency in spoken English * Between 60-85 years old * No neurological or psychiatric disorders * No substance abuse * Not taking anti-depressants * Not taking anti-anxiety medication * No history of seizures * No color blindness * No glaucoma * No macular degeneration * No amblyopia (lazy eye) * No strabismus (cross eyed) * Aneurysm clip(s) * No Cardiac pacemaker * No Implanted cardioverter defibrillator (ICD) * No Electronic implant or device * No Magnetically-activated implant or device * No Neurostimulation system * No Spinal cord stimulator * No Internal electrodes or wires * No Bone growth/bone fusion stimulator * No Cochlear, otologic, or other ear implant * No Insulin or other infusion pump * No Implanted drug infusion device * No type of prosthesis (eye, penile, etc.) * No Heart valve prosthesis * No Eyelid spring or wire * No Artificial or prosthetic limb * No Metallic stent, filter, or coil * No Shunt (spinal or intraventricular) * No Vascular access port and/or catheter * No Radiation seeds or implants * No Swan-Ganz or thermodilution catheter * No Medication patch (Nicotine, Nitroglycerine) * No metallic fragment or metallic foreign body in/on the body that can not be removed * No Wire mesh implant * No Tissue expander (e.g., breast) * No Surgical staples, clips, or metallic sutures * No Joint replacement (hip, knee, etc.) * No Bone/joint pin, screw, nail, wire, plate, etc. * No IUD, diaphragm, or pessary * No Dentures or partial plates that can not be removed * No Tattoo or permanent makeup * No Body piercing jewelry * No Claustrophobia

Interventions

DEVICE

MediTrain

DEVICE

wrist worn multi-sensor watches

DEVICE

Sleep monitor

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Conditions

MCIAging

Locations

University of California, San Francisco

San Francisco, California 94158

United States