Back to Trials
NCT06651736NARecruiting

Optimizing Low Vision Rehabilitation in Emotionally Distressed Patients With Inherited Retinal Diseases

University of Michigan

Start Date

1/13/2025

Completion Date

11/24/2028

Summary

The purpose of this study is to understand if combining Low Vision Rehabilitation (LVR) with Emotional Regulation Therapy (ERT) can help people with inherited retinal diseases (IRDs) that experience emotional distress related to participants' vision loss. The study team hypothesize that treatment with LVR will produce measurable functional gains and that these effects will be enhanced by ERT-linked improvement among the subgroup of IRD patients with elevated vision-related anxiety.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Diagnosed with vision impairment with IRD etiology * Must have had a clinical exam with an IRD specialist within the three months of assignment to Arm * Have had a Goldmann visual field that was tested with III-4e isopter within the last year * Have a disability greater than zero theta in any of the domains of Michigan Retinal Dystrophy Questionnaire (MRDQ) * Have an indication from the IRD specialist that the ocular condition will not deteriorate over the next 1- year * Able to participate in 10 weeks of ERT sessions while being physically located in Michigan (these will take place in the first 10 months of the study) Exclusion Criteria: * Having other ocular comorbidities including those associated with an IRD such as control of cystoid macular edema (CME) * Functional needs regarding low vision (i.e. activities of daily living) have been adequately addressed per a study low vision specialist * Current mental health therapy * The participant must not have an elevated suicidal intention (SI) or suicide risk based on Patient Health Questionnaire (PHQ-9) further information collected at screening (If suicidal intentions are identified, the study staff will complete the suicide protocol (per protocol) * If the participant is using medication for mental health or psychiatry concerns, participants must be on a stable dose of the medication (1-month of taking), otherwise will be excluded * Inability to complete study task requirements

Interventions

BEHAVIORAL

Low Vision Rehabilitation (LVR)

BEHAVIORAL

Emotion Regulation Therapy (ERT)

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Inherited Retinal Diseases

Locations

University of Michigan

Ann Arbor, Michigan 48105

United States