A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
Start Date
11/21/2024
Completion Date
10/30/2028
Summary
This is a multi-center, open-label study to investigate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary activity of REC-1245 administered orally on a once daily (QD) schedule in participants with unresectable, locally advanced, or metastatic solid tumors.
Detailed Description
The purpose of this study is to investigate the safety, tolerability and pharmacokinetics of REC-1245 for the treatment of participants with unresectable locally advanced or metastatic solid tumors. Participants will receive treatment with REC-1245 for up to 2 years.
Eligibility Criteria
Age Range: 12 years to No maximum
Interventions
REC-1245
Conditions
Locations
City of Hope
Duarte, California 91010
United States
Cleveland Clinic
Cleveland, Ohio 44195
United States
SCRI Oncology Partners - PPDS
Nashville, Tennessee 37203
United States
START Mountain Region
West Valley City, Utah 84119
United States
Princess Margaret Cancer Centre
Toronto, Ontario M5G 1X6
Canada
McGill University Health Centre (MUHC) - The Montreal
Québec, H4A3J1
Canada