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NCT06698146Recruiting

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Northwestern University

Start Date

8/27/2025

Completion Date

1/1/2035

Summary

Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal of this study is to look at and compare the clinical results of all the different approved methods (living vs. Deceased, whole organ vs. Split, one staged vs. Two staged) used to perform a standard liver transplant procedure for recipients with CRLM. Investigators will look at things like different procedure results, recovery in the hospital, and survival rates one year after the transplant. Investigators will also take blood samples from participants to be used in future research. All the transplant methods the investigators are comparing are standard practices approved by the United Network of Organ Sharing (UNOS).

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion: 1. All Patients of either gender ≥ 18 years of age who are listed for Liver transplant candidates at Northwestern with liver metastases due to colorectal cancer (CRLM). 2. Subjects must be able to provide informed consent themselves and without the use of a legally authorized representative (LAR), to be determined by the PI or Sub-I at the time of Consent. Exclusion: 1. Adults unable to consent 2. Pregnant Women 3. Certain clinical/surgical/anatomical parameters, at the discretion of the PI.

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Conditions

Liver Transplant SurgeryColorectal Cancer MetastaticColon Cancer Liver Metastases

Locations

Northwestern University-Comprehensive Transplant Center

Chicago, Illinois 60611

United States