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NCT06719180PHASE4Recruiting

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

MediSys Health Network

Start Date

12/1/2024

Completion Date

10/31/2025

Summary

The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less immediate postoperative pain medication and increase patient comfort/satisfaction.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patients 18 years and older requiring total laparoscopic hysterectomy with or without bilateral salpingo-oophorectomy for benign conditions * Presence of malignancy Exclusion Criteria: * Conversion to laparotomy * Previous multiple abdominal and/or pelvic surgeries * Significant medical comorbidities or cardiac history * Poor initial Aldrete score4 (\<10) * Significant pre-op pain medication use * Contraindication to any medication that would be used in the study (Bupivacaine, epinephrine, tramadol or oxycodone)

Interventions

DRUG

Bupivacain

OTHER

Saline (NaCl 0,9 %) (placebo)

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Conditions

HysterectomyPost Operative Analgesia

Locations

Flushing Hospital Medical Center

Flushing, New York 11355

United States