Back to Trials
NCT06754176NARecruiting

Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation

University of California, San Francisco

Start Date

4/17/2025

Completion Date

8/1/2029

Summary

The goal of this study is to assess the short-term effects of minimal and moderate drinking on atrial fibrillation (AFib) episodes in a real-world population diagnosed with 'come-and-go'/paroxysmal AFib. The question it aims to answer is: Is there a greater occurrence of AFib episodes when participants are allowed to consume alcohol according to random assignment? Participants will: * Be given daily random assignments to avoid or not to avoid alcohol * Wear an adhesive electrocardiographic (ECG) heart monitor * Wear a wrist-worn fitness tracker * Wear an anklet transdermal alcohol monitor * Wear an adhesive glucose monitor * Complete morning and evening surveys daily Participants may be compensated up to $50 for full completion of the study. This study can be done in-person or remote.

Detailed Description

This study is a case-crossover randomized trial, where each participant will be instructed to avoid or not avoid drinking alcohol on randomly assigned days during a 14-day monitoring period. Participants will also wear an external ECG monitor, an alcohol monitor, a continuous glucose monitor, and a fitness tracker for up to two weeks while utilizing a mobile application to receive daily instructions/reminders on drinking and short surveys. The investigators will compare participant self-report of alcohol consumption, glucose monitoring, fitness levels, sleep health, and heart rhythm data in order to better understand the immediate relationship between drinking alcohol and heart rhythm. A total of 100 participants will be enrolled.

Eligibility Criteria

Age Range: 21 years to No maximum

Inclusion Criteria * Comfortable reading and writing in English * Have a smartphone and willing and able to use the Eureka mobile application * Currently diagnosed with paroxysmal AFib without a plan to change their AFib management during the two-week monitoring period * At least one episode of AFib in the past month OR, in the judgement of a healthcare provider, could potentially have one episode of AF in the next month * Drank alcohol at least 1 day/week on average in the past month * Willing and able to be randomly assigned daily to avoid or not avoid drinking alcohol over a 2-week period * Willing and able to provide written informed consent Exclusion Criteria * Only post-operative AFib * Greater than 40% ventricular pacing * History of alcohol addiction or abuse determined by self-reported history or AUDIT-C score * Intolerance to alcohol * History of liver disease * Currently incarcerated * Currently pregnant or trying to get pregnant

Interventions

BEHAVIORAL

Alcohol Consumption Randomized Instructions

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Atrial Fibrillation (AF)Atrial Fibrillation (Paroxysmal)

Locations

UCSF Medical Center at Parnassus

San Francisco, California 94143

United States

UCSF Medical Center at Mission Bay

San Francisco, California 94158

United States