Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
Start Date
4/16/2025
Completion Date
3/1/2027
Summary
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA). In this randomized controlled trial, three analgesic regimens following DRGA in Franciscan Children's Hospital will be compared using both self-report and behavioral measures. The analgesic therapies to be investigated are ibuprofen monotherapy, alternating ibuprofen and acetaminophen dual-therapy, and combined ibuprofen and acetaminophen dual-therapy. For the purposes of this study, combined therapy is defined as the simultaneous administration of acetaminophen and ibuprofen at regular intervals, whereas alternating therapy is defined as one analgesic (acetaminophen or ibuprofen) administered within a 3 hour interval of the other.
Eligibility Criteria
Age Range: 4 years to 6 years
Interventions
Ibuprofen
Acetominophen
Conditions
Locations
Franciscan Children's Hospital
Brighton, Massachusetts 02135
United States