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NCT06770062Recruiting

Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

Mayo Clinic

Start Date

1/20/2025

Completion Date

12/1/2027

Summary

The purpose of this research is to determine the feasibility of a larger, future study proposing a multimodal approach using cardiac CT and MRI to assess the risk of developing left ventricular (LV) systolic dysfunction in patients with mitral regurgitation (MR).

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Age \>= 18 * Male or Female * A diagnosis of severe chronic primary mitral regurgitation * Undergoing isolated robotic mitral annuloplasty at Mayo Clinic Rochester * Patients must have the ability to consent or have an appropriate representative available to do so. Exclusion Criteria: * Prior valve intervention, * Concomitant valve surgery at the time of mitral annuloplasty (e.g. tricuspid annuloplasty, aortic valve replacement). * Concomitant \>= moderate regurgitation or stenosis in any other valve by preoperative echocardiography * History of prior myocardial infarction * History of cardiomyopathy unrelated to mitral regurgitation (e.g. dilated, hypertrophic, infiltrative) * Pregnancy. Women of childbearing potential will be verbally screened by clinical staff during as part of routine pre-MRI evaluation. If a subject is unsure whether they could be pregnant, a negative pregnancy test will be performed prior to scanning. * Implantable devices that would be a contraindication to MRI * Severe allergy to gadolinium MRI contrast

Interventions

DIAGNOSTIC_TEST

Cardiac MRI

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Conditions

Left Ventricular Systolic Dysfunction

Locations

Mayo Clinic

Rochester, Minnesota 55905

United States