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NCT06785324NARecruiting

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

University of Chicago

Start Date

5/12/2025

Completion Date

11/6/2027

Summary

This clinical trial aims to assess the effect of nutrition and exercise on muscle and adiposity in adults with Philadelphia Chromosome (Ph) Negative B-ALL undergoing inpatient induction therapy. Participants will take part in 2 different interventions: * Nutrition Intervention * Physical Exercise Intervention All subjects will be provided with a wearable electronic activity monitor (FitBit®) to assist in recording activity levels in minutes of activity.

Eligibility Criteria

Age Range: 18 years to 50 years

Inclusion Criteria: * New Diagnosis of Philadelphia Chromosome Negative B-ALL * Receiving intensive pediatric-inspired induction chemotherapy Exclusion Criteria: * BMI ≤18.5 kg/m2 at time of diagnosis * Unable to comply with both the recommended diet and exercise regimen as deemed by the research or treatment team * Pregnant

Interventions

BEHAVIORAL

Nutrition Intervention

BEHAVIORAL

Exercise intervention

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Conditions

Philadelphia Chromosome NegativeB Cell Acute Lymphoblastic Leukemia (B-ALL)B-ALL

Locations

University of Chicago Medicine Comprehensive Cancer Center

Chicago, Illinois 60637

United States