NCT06789770Recruiting
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
University of Pennsylvania
Start Date
11/20/2024
Completion Date
12/1/2026
Summary
This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.
Detailed Description
As part of standard of care, a drug-induced sleep endoscopy will be done, where route of breathing will be determined as a percentage of total breaths (during baseline, lateral sleep and maneuver). As part of the research procedure, an in-laboratory Polysomnogram will be conducted as study procedure including a oronasal pressure signal cannula to assess route of breathing.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* • Adults (≥ 18yrs) that underwent clinical evaluation at the CPAP Alternatives Clinic at Penn Otorhinolaryngology.
* Must have at least mild OSA (AHI\>5)
Exclusion Criteria:
* • Sleep study with an AHI\<5, \>25% of total events being central or mixed events, or inability to achieve adequate drug-induced sleep.
* Upper Respiratory Illness at the time of the DISE.
Conditions
Sleep Apnea, Obstructive
Locations
Hospital at the University of Pennsylvania
Philadelphia, Pennsylvania 19104
United States