NCT06793644Recruiting

Study of ICG Fluorescence Imaging in Open Fracture and Infection Patients

Dartmouth-Hitchcock Medical Center

Start Date

6/10/2025

Completion Date

10/1/2027

Summary

The purpose of this study is to determine whether an indocyanine green (ICG) fluorescence imaging system (cBPI) can be used to provide surgeons with information about bone health or bone blood flow. This will help surgeons better understand the healing potential of bone and relative risk of complication. This is important to help surgeons select the most appropriate treatment for severe traumatic injuries and infections.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patients 18 years of age or older. * Open extremity fracture, planning for management with external fixation, internal fixation or joint fusion. * Fracture Related Infection, planning for management with debridement and possible removal of hardware. * Will have all planned fracture care surgeries performed by a participating surgeon or delegate. * Provision of informed consent. Exclusion Criteria: * Inability of patient to provide informed consent * Fracture of the hand. * Iodine allergy. * Burns at the fracture site.

Interventions

DRUG

Immunofluorescence Imaging

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Conditions

Fractures, BoneTrauma Injury

Locations

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire 03756

United States