NCT06805630NARecruiting

Urine Methylation Markers in UTUC

Duke University

Start Date

5/7/2025

Completion Date

6/30/2026

Summary

This is a research study to measure DNA markers in the urine of patients with upper tract urothelial cancer (UTUC) before surgery and during follow-up visits. Identifying these DNA markers could improve diagnosis before surgery, help assess risk, and predict early recurrence of the cancer. Urine samples will be de-identified and sent to Pangea Laboratory LLC for analysis. The results of this test will be compared to the traditional tests in upper tract urothelial cancer, such as cells in the urine and tissue biopsy.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * \>=18 years * Primary UTUC Exclusion Criteria: * Patients who do not understand and/or are unwilling to sign a written informed consent

Interventions

DIAGNOSTIC_TEST

Bladder CARE™

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Conditions

Upper Tract Urothelial Cancer

Locations

Duke University

Durham, North Carolina 27710

United States