NCT06828159NARecruiting

Dietary Wild Blueberries and Joint Health

University of Nevada, Las Vegas

Start Date

9/1/2025

Completion Date

3/1/2028

Summary

The goal of this proposed study is to examine the effects of dietary wild blueberries on gut microbiome, serum markers of inflammation, and joint function in adults. Each participant will consume 25g freeze-dried blueberries or matched placebo powder for 12 weeks, with a 2-week washout phase between.

Eligibility Criteria

Age Range: 40 years to 75 years

Inclusion Criteria: * Adults with documented multi-joint/knee arthritis Exclusion Criteria: * inability to give informed consent * pregnancy or lactation * planned knee replacement surgery * allergy or contraindication to berries * recent trauma of the knee responsible of the symptomatic knee * intra-articular injection in the target knee/hip in the last 3 months * oral corticosteroid therapy ≥ 5 mg/day (prednisone equivalent) at baseline * use of berry extracts in the last 3 months * special diets * cancer treatment * bone diseases

Interventions

DIETARY_SUPPLEMENT

Wild blueberry

DIETARY_SUPPLEMENT

Placebo

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Conditions

Gut -MicrobiotaInflammation BiomarkersPain AssessmentJoint Pain

Locations

OMRF

Oklahoma City, Oklahoma 73104

United States