NCT06830174NARecruiting
tDCS for Laryngeal Dystonia
Yale University
Start Date
4/14/2025
Completion Date
12/1/2026
Summary
This project will apply transcranial direct current stimulation (tDCS) to multiple brain areas to evaluate the effects as a potential treatment for laryngeal dystonia (formerly spasmodic dysphonia).
Detailed Description
Baseline neuroimaging data will be acquired from all participants via MRI, EEG. Each participant will be seen for multiple testing sessions over a five day period. LD participants will undergo the neuromodulation (HD-tDCS Stimulation) for twenty minutes while engaged in watching videos/movies or performing a word production task.
Eligibility Criteria
Age Range: 18 years to 65 years
Inclusion Criteria:
* Participants must be clinically evaluated for the diagnosis of LD or have the proof of LD diagnosis. (Not applicable for control participants)
* No other known or history of speech, voice disorder other than LD.
* Provision of signed and dated informed consent form.
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Must not be pregnant.
Exclusion Criteria:
* All individuals who do not meet the above mentioned criteria are excluded from the study.
* Subjects with a history of epilepsy or depression or is claustrophobic.
Interventions
DEVICE
Starstim system
Conditions
Laryngeal Dystonia
Locations
Yale University
New Haven, Connecticut 06511
United States