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NCT06843538PHASE3Recruiting

Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery

TriHealth Inc.

Start Date

2/3/2025

Completion Date

6/1/2026

Summary

The purpose of this research study is to determine if taking tamsulosin preoperatively decreases your chances of being discharged after surgery with a Foley catheter (flexible tube that drains urine from the bladder into a collection bag).

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: \- Patients undergoing any pelvic organ prolapse repair or incontinence surgery Exclusion Criteria: * Any surgery involving a non-urogynecologist * Patients already on an alpha blocker * Baseline hypotension * History of syncope * Postural orthostatic tachycardia syndrome (POTS) * Non-English speaker or interpreter unavailable for Spanish-speaking patient * Impaired cognition impeding proper consenting * Any other medical contraindication for tamsulosin use * History of urinary retention requiring continuous or intermittent catheterization * Patients consented for the study but then due to intraoperative complication, routine voiding trial no longer indicated due to requiring indwelling catheter or intermittent catheterization on discharge will be excluded from primary outcome analysis * Pregnancy

Interventions

DRUG

Tamsulosin

DRUG

Placebo

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Conditions

Postoperative Urinary Retention (POUR)

Locations

TriHealth

Cincinnati, Ohio 45220

United States