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NCT06854198NARecruitingAccepts Healthy Volunteers

Glaucoma Screening to Enhance At-Risk Californians' Health

University of California, San Francisco

Start Date

2/10/2026

Completion Date

9/1/2029

Summary

The vast majority of glaucoma cases in the United States go undetected and untreated until the late stages of the disease. Open-angle glaucoma is a progressive condition that is asymptomatic in its early to moderate stages and may be amenable to screening through telemedicine-based approaches. This study is a randomized trial to evaluate whether glaucoma screening with established tests (e.g., optical coherence tomography, fundus photography, and tonometry) is more effective for detecting undiagnosed glaucoma cases compared to education alone or delayed intervention.

Detailed Description

Specific Aim 1: To determine the effectiveness of a telemedicine-based glaucoma screening program for detecting glaucoma. The investigators hypothesize that a mobile screening intervention incorporating optical coherence tomography (OCT), fundus photography, and tonometry will result in a greater number of new glaucoma diagnoses compared to education alone or delayed treatment. Specific Aim 2: To determine whether a telemedicine-based glaucoma screening program provides benefits beyond glaucoma detection. The investigators hypothesize that (A) individuals randomized to the screening intervention will have higher rates of cataract surgery and distance vision correction one year after screening, and (B) those in the screening intervention will report higher vision-related quality of life one year after screening.

Eligibility Criteria

Age Range: 50 years to No maximum

Inclusion Criteria: * Black people aged 50 years or older * Hispanic people aged 65 years or older * People with diabetes aged 50 years or older * Must have been seen at the Federally Qualified Health Center (FQHC) within the past month Exclusion Criteria: * Patients without a valid phone number or mailing address * Patients who have had an optometry appointment within the past year

Interventions

OTHER

Glaucoma screening with optical coherence tomography (OCT), color fundus photography, and tonometry

OTHER

Educational Brochure

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Conditions

Glaucoma

Locations

Baywell Health

Oakland, California 94607

United States

University of California, San Francisco

San Francisco, California 94158

United States