NCT06859918NARecruiting

Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

University of Pennsylvania

Start Date

3/24/2025

Completion Date

12/1/2027

Summary

The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings. The Investigators will test the efficacy of TUNE In to improve social functioning in adults with autism spectrum disorder (ASD), using a randomized controlled trial using the SRS-2 as the primary outcome measure.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * 18 years of age or older * Meet ASD diagnostic criteria supported by an outside diagnostic evaluation and/or by the clinical and developmental information gathered from a phone screen * Be willing to complete screening surveys (outcome measures) * Social Responsiveness Score, Second Edition, self-report SRS survey score of greater than or equal to 60 Exclusion Criteria: * Severe self-injurious or aggressive behaviors; or with suicidal or homicidal ideation or behaviors (e.g. suicide attempt) within the last 6 months * Major mood episode (major depressive episode, manic episode), psychotic symptoms, or a psychiatric hospitalization within the last 6 months * A history of intellectual disability or low Shipley-2 score

Interventions

BEHAVIORAL

TUNE In: Training to Understand and Navigate Emotions and Interactions

Interested in This Trial?

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Conditions

Autism Spectrum DisorderAutismAutistic DisorderAsperger Syndrome

Locations

Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania

Philadelphia, Pennsylvania 19104

United States